Medical Science
Combining Low-Sodium Intake with DASH Diet Significantly Cuts Cardiovascular Risks
2025-04-23

A groundbreaking study published in the American Journal of Preventive Cardiology has revealed that integrating a low-sodium diet with the Dietary Approaches to Stop Hypertension (DASH) eating plan can reduce the risk of cardiovascular diseases by over 14%. This innovative approach offers particularly substantial benefits for women and Black adults dealing with high blood pressure. By analyzing data from the United States, researchers explored how sodium reduction, either independently or paired with the DASH diet, influences the likelihood of developing atherosclerotic cardiovascular disease (ASCVD) within a decade. The findings suggest that adherence to both strategies yields the most significant health advantages.

Details of the Study and Its Outcomes

In a meticulously designed randomized trial conducted between 1997 and 1999 across four clinical sites in the U.S., scientists examined the effects of varying sodium levels combined with dietary patterns on cardiovascular risks. Participants, all adults with elevated blood pressure, were randomly assigned to follow either the DASH diet or an average American diet over a span of 12 weeks. During this period, they consumed three different sodium levels—high, medium, and low—in random sequences, each lasting approximately 30 days. The highest sodium level mirrored typical American consumption, while the lowest was below recommended intakes.

The primary outcome measure was the ASCVD risk score calculated using the Pooled Cohort Equation (PCE). Among the 390 participants, those adhering to the DASH diet experienced a more pronounced reduction in estimated ASCVD risk compared to the control group, showcasing an absolute difference of -0.12% and a relative difference of -5.33%. When sodium intake was reduced, especially at lower levels, there was an even greater decrease in ASCVD risk. Combining the DASH diet with low sodium intake led to the most significant drop in ASCVD risk, achieving an absolute difference of -0.35% and a relative difference of -14.09% compared to the high-sodium control diet.

Further stratified analyses highlighted stronger sodium reduction impacts among women, Black adults, and individuals with stage 2 hypertension. These results underscore the importance of personalized dietary interventions based on demographic and health factors.

It is essential to recognize that while the study provided valuable insights into short-term changes in ASCVD risk scores, it did not address the long-term implications of sustained dietary modifications due to the brief intervention periods.

From a journalist's perspective, this research serves as a powerful reminder of the critical role that diet plays in managing and preventing cardiovascular diseases. It emphasizes the need for tailored nutritional strategies that consider individual differences, such as gender and race, to maximize health outcomes. Moreover, it highlights the necessity for future studies to explore extended intervention durations and broader participant ranges to further validate these findings and refine sodium intake recommendations.

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