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1 p.m. ET Games

In the 1 p.m. ET games, there are several key players with injury concerns. Ja’Tavion Sanders, the TE for CAR, has a neck issue listed as questionable. However, he had a full practice on Friday, which gives hope for a potential start on Sunday. On the other hand, Jalen Coker, the WR for CAR, is doubtful with a quad injury. If he can't play, David Moore might become a "dart throw for the desperate."

Cedric Tillman, the WR for CLE, is out with a concussion. This means Jerry Jeudy and Elijah Moore could see a few extra passes. Jamari Thrash, also a WR for CLE, is questionable with a shoulder injury. If he can play, Tillman's absence provides him with an opportunity for some targets.

Trevor Lawrence, the QB for JAX, is out with a concussion and has been placed on IR. Mac Jones will finish the season as the starting quarterback in Jacksonville.

Alexander Mattison, the RB for LV, is questionable with an ankle injury. He practiced in limited fashion all week, but it may not be enough for him to take the field on Sunday. Zamir White, the RB for LV, is out with a quad injury, extending Sincere McCormick's fantasy relevance.

Jakobi Meyers, the WR for LV, is questionable with an ankle injury. All signs point to him playing, but it's always a concern. Raheem Mostert, the RB for MIA, is questionable with a hip injury and is not expected to play. Jaylen Wright could get some extra touches in his absence.

Will Reichard, the K for MIN, is questionable with a quad injury. He was activated from IR and the fill-in John Parker Romo was released.

Kendre Miller, the RB for NO, is questionable with a hamstring injury. He was also activated from IR and could handle a small share of the team's backfield touches. Taysom Hill, the TE for NO, is out with a knee injury and is on IR. This is especially significant given his multifaceted role on the team.

Bub Means, the WR for NO, is out with an ankle injury and is on IR. Marquez Valdes-Scantling is now the only serious Saints WR option.

Malik Nabers, the WR for NYG, is questionable with a groin injury. It could be a game-time decision. Wan’Dale Robinson and Darius Slayton would likely get more looks if Nabers sits.

Breece Hall, the RB for NYJ, is out with a knee injury. Braelon Allen and Isaiah Davis will try to pick up the slack.

Dallas Goedert, the TE for PHI, is out with a knee injury and is on IR. Grant Calcaterra takes over at TE as Goedert attempts to heal in time for the playoffs.

George Pickens, the WR for PIT, is questionable with a hamstring injury. His late-week addition to the injury report is concerning. Calvin Austin III (concussion) is ready to return and could benefit.

Bucky Irving, the RB for TB, is questionable with a hip injury. If the team decides to give him a week off, Sean Tucker would see a lot more action.

Trey Palmer, the WR for TB, is questionable with a hip injury. On the positive side, Mike Evans (hamstring/calf) was removed from the injury report and will play.

4 p.m. ET Games

In the 4 p.m. ET games, Dalton Kincaid, the TE for BUF, is questionable with a knee injury. If he's not fully ready to return, Dawson Knox will handle most of the TE duties.

Keon Coleman, the WR for BUF, is questionable with a wrist injury. If he sits, Curtis Samuel (foot) is back and ready to step in.

Roschon Johnson, the RB for CHI, is out with a concussion. This leads to a huge increase in Travis Homer's fantasy value. D’Andre Swift, also a RB for CHI, is questionable with a quad injury. If he can't play, Homer's value could grow even more.

DJ Moore, the WR for CHI, is questionable with a quad injury. He says he will play, but it's always a risk. Keenan Allen (ankle) was removed from the injury report.

Tyler Higbee, the TE for LAR, is out with a knee injury. It remains to be seen when he will return.

Kenneth Walker III, the RB for SEA, is out with an ankle injury. This means Zach Charbonnet could become a popular waiver wire pickup in the almost 50% of leagues where he was available.

Jordan Mason, the RB for SF, is out with an ankle injury and is on IR. Isaac Guerendo will now back up Patrick Taylor Jr. as both Mason and Christian McCaffrey are on IR.

Sunday Night Game

In the Sunday night game, Mecole Hardman, the WR for KC, is out with a knee injury and is on IR. Hollywood Brown could be back in action in Week 16.

Ladd McConkey, the WR for LAC, is questionable with a knee injury. Given the late start and the optimism surrounding his recovery, you may want to be cautious.