Wednesday night proved to be a thrilling affair in the world of hoops. The No. 1 and No. 2 teams faced setbacks away from home, while the two-time defending national champions bounced back from a rough stretch. Here's a detailed look at the key matchups and what they mean.

Creighton Stuns No. 1 Kansas

The unranked Creighton Bluejays pulled off a major upset by defeating the No. 1 Kansas Jayhawks 76-63. This is the second consecutive season that Creighton has knocked off a No. 1 team at home, following their win over Dan Hurley's Huskies last year in Omaha. After a tough 0-3 stretch in late November, the Bluejays found their rhythm and secured a 13-point win over Bill Self's unbeaten team. The home crowd was electric, with Creighton leading 41-31 at halftime. Kansas made a comeback early in the second half but was quickly shut down as Creighton went on an 11-0 run. Creighton's guard Pop Isaacs was on fire, shooting 41% from beyond the arc and leading the game with 27 points. Kansas standout Hunter Dickinson was surprisingly quiet, scoring only six points on four shots.The Bluejays maintained their lead for the rest of the game and eventually won by 16 points. Kansas turned the ball over only five times but was unable to capitalize, scoring only 12 points off those turnovers.

No. 9 Duke Holds Off No. 2 Auburn

Duke emerged victorious in a top-10 matchup, handing Auburn its first loss of the season. The Blue Devils led 43-36 at halftime and never looked back. They led by as much as 12 points in the second half but had to fend off a late Auburn comeback. Auburn's offense went cold in the final minutes, going 4-16 from the field in the last seven minutes. Duke's Cooper Flagg was a standout, scoring 22 points, grabbing 11 rebounds, and dishing out four assists. Auburn's center Johni Broome matched Flagg with a double-double of 20 points and 12 rebounds.The Blue Devils' fast-paced offense paid off, recording 16 fast break points compared to Auburn's zero. Duke will open ACC play against Louisville on Sunday, while Auburn will travel home to face Richmond.

No. 6 Iowa State Beats No. 5 Marquette

Iowa State remained undefeated at home by defeating Marquette 81-70. The Cyclones led 46-37 at halftime and held off the Golden Eagles in the second half. Marquette made a late push, tying the game at 61-61 with nine minutes to play, but Iowa State responded with a 14-0 run to secure the win. Iowa State's efficient offense was a key factor, shooting 51% from the field compared to Marquette's 39%. Keshon Gilbert led the way for Iowa State with 24 points and eight assists. Marquette star Kam Jones struggled, going 6-21 from the field and 1-5 from beyond the arc.The Golden Eagles will look to bounce back at home against No. 11 Wisconsin on Saturday, while the Cyclones will face Jackson State on Sunday.

No. 25 UConn Outlasts No. 15 Baylor

The UConn Huskies got a much-needed win over Baylor, improving to 6-0 at home. After a rough Maui Invitational where they lost three out of four games, UConn bounced back on Wednesday night. The Huskies trailed by double-digits in the first half but cut the lead to one by halftime. In the second half, it was a tight battle, with neither team able to pull away. However, UConn capitalized on Baylor's mistakes, scoring 21 points off 10 turnovers. UConn also had a better showing from the charity stripe, recording 26 points compared to Baylor's 12.Freshman Liam McNeeley led UConn with 17 points, eight rebounds, and three blocks. Baylor's guard Robert Wright was impressive, going 9-15 from the field with four assists. UConn will look to build on this win as they face Texas, No. 7 Gonzaga, and Xavier in their next three matchups.